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Company Name: Hebei Tianxu Biotech Co.,Ltd.
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Curcumin CAS 458-37-7
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Curcumin Basic information
Product Name:Curcumin
Synonyms:Curcumin (mixture of curcumin;TURMERIC EXTRACT;1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(e,e)-6-heptadiene-3;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-6-heptadiene-3;6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-1;curcuma;haidr
CAS:458-37-7
MF:C21H20O6
MW:368.38
EINECS:207-280-5
Product Categories:Miscellaneous Natural Products;Analytical Chemistry;Antioxidant;Biochemistry;Indicator (pH);pH Indicators;Colorants;Natural Plant Extract;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Diferuloylmethane, Natural Yellow 3, C.I. 75300;pigment
Mol File:458-37-7.mol
Curcumin Structure
Curcumin Chemical Properties
Melting point 183 °C
density 0.93
vapor density 13 (vs air)
refractive index 1.4155-1.4175
storage temp. −20°C
solubility ethanol: 10 mg/mL
form powder
Colour Index 75300
color orange
Water Solubility Slightly soluble (hot)
Merck 14,2673
BRN 2306965
Stability:Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference458-37-7(CAS DataBase Reference)
EPA Substance Registry System1,6-Heptadiene-3, 5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-(458-37-7)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38-11
Safety Statements 26-36-16-7
WGK Germany 2
RTECS MI5230000
Hazard Note Irritant
TSCA Yes
HS Code 29145000
Hazardous Substances Data458-37-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
C.I. 75300English
Curcumin Usage And Synthesis
Chemical Propertiesorange crystalline powder
UsageA natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Usageantiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor
UsageCurcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The curcuminoids are polyphenols and are responsible for the yellow color of turmeric. Curcumin can exist in at least two t
General DescriptionOrange-yellow needles.
Air & Water ReactionsSlightly soluble in hot water .
Reactivity ProfileCurcumin is sensitive to light and changes in pH. Curcumin may react with oxidizing materials.
Biological ActivityAntitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF α , IL-1, IL-6, PKC, EGFR, NF- κ B, I κ B kinase and more. Upregulates expression of PPAR γ , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo .
Curcumin Preparation Products And Raw materials
Raw materialsEtanol-->Acetic anhydride-->Water-->2,4-Pentanedione-->Vanillin-->METHYL CHLORIDE-->1,2-Propanediol-->Butylamine-->Tributyl borate-->TURMERIC 1G [R]-->Curcuma oil-->Curcuma powder

 

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  • Copyright Hebei Tianxu Biotech Co.,Ltd. E-mail: exporter@curcumin-factory.com Export Dept.Tel: 0086-310-8718866 / 8710888 Mobil: +86-13932026279
    Website: http://www.curcumin-factory.com Addr: High-new technology industrial park, Quzhou, Handan, Hebei, China
    Main Product: curcumin, capsanthin, capsicum oleoresin, black pepper oleoresin, gromwell pigment.